Negative regulation of Stat3 by activating PTPN11 mutants contributes to the pathogenesis of Noonan syndrome and juvenile myelomonocytic leukemia. [electronic resource]
Producer: 20090914Description: 22353-22363 p. digitalISSN:- 0021-9258
- Animals
- Flow Cytometry -- methods
- Gene Expression Regulation, Leukemic
- Humans
- Leukemia, Myelomonocytic, Juvenile -- genetics
- Mice
- Models, Biological
- Mutation
- Noonan Syndrome -- pathology
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 -- genetics
- STAT3 Transcription Factor -- metabolism
- Tyrosine -- chemistry
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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