The interleukin-15 system suppresses T cell-mediated autoimmunity by regulating negative selection and nT(H)17 cell homeostasis in the thymus. [electronic resource]
Producer: 20150916Description: 118-29 p. digitalISSN:- 1095-9157
- Animals
- Antigen-Presenting Cells -- immunology
- Autoantibodies -- blood
- Autoimmunity -- genetics
- CD4-Positive T-Lymphocytes -- immunology
- Clonal Selection, Antigen-Mediated
- Female
- Gene Expression
- Homeostasis
- Immunophenotyping
- Interleukin-15 -- deficiency
- Interleukin-15 Receptor alpha Subunit -- deficiency
- Lymph Nodes -- immunology
- Lymphocyte Activation -- genetics
- Mice
- Mice, Knockout
- Phenotype
- Radiation Tolerance -- genetics
- Salivary Glands -- immunology
- T-Lymphocyte Subsets -- immunology
- Th17 Cells -- immunology
- Thymocytes -- immunology
- Thymus Gland -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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