Pygo2 activates MDR1 expression and mediates chemoresistance in breast cancer via the Wnt/β-catenin pathway. [electronic resource]
Producer: 20170831Description: 4787-97 p. digitalISSN:- 1476-5594
- ATP Binding Cassette Transporter, Subfamily B -- genetics
- Animals
- Breast Neoplasms -- drug therapy
- Doxorubicin -- administration & dosage
- Drug Resistance, Neoplasm -- genetics
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Intracellular Signaling Peptides and Proteins -- genetics
- MCF-7 Cells
- Mice
- Neoplastic Stem Cells -- metabolism
- Transcriptional Activation -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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