Discovery and characterization of pseudocyclic cystine-knot α-amylase inhibitors with high resistance to heat and proteolytic degradation. [electronic resource]
Producer: 20141203Description: 4351-66 p. digitalISSN:- 1742-4658
- Amino Acid Sequence
- Animals
- Apocynaceae -- chemistry
- Crystallography, X-Ray
- Drug Discovery
- Enzyme Inhibitors -- chemistry
- Hot Temperature
- Humans
- Hydrogen Bonding
- Insect Proteins -- antagonists & inhibitors
- Molecular Docking Simulation
- Molecular Dynamics Simulation
- Molecular Sequence Data
- Plant Leaves -- chemistry
- Plant Proteins -- chemistry
- Protein Binding
- Protein Engineering
- Protein Stability
- Protein Structure, Tertiary
- Proteolysis
- Solutions
- Tenebrio -- enzymology
- alpha-Amylases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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