Elevated mutant dynorphin A causes Purkinje cell loss and motor dysfunction in spinocerebellar ataxia type 23. [electronic resource]
Producer: 20151116Description: 2537-52 p. digitalISSN:- 1460-2156
- Action Potentials -- physiology
- Age Factors
- Animals
- Animals, Newborn
- Cell Count
- Cells, Cultured
- Cerebellum -- pathology
- Disease Models, Animal
- Dynorphins -- genetics
- Gene Expression Regulation -- genetics
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Movement Disorders -- etiology
- Mutation -- genetics
- Patch-Clamp Techniques
- Purkinje Cells -- physiology
- Signal Transduction -- genetics
- Spinocerebellar Degenerations -- complications
- Synapses -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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