5-Aza-2'-deoxycytidine restores proapoptotic function of p53 in cancer cells resistant to p53-induced apoptosis. [electronic resource]
Producer: 20080814Description: 680-8 p. digitalISSN:- 1532-4192
- Antimetabolites, Antineoplastic -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- metabolism
- Azacitidine -- analogs & derivatives
- Cell Cycle -- drug effects
- Cell Proliferation -- drug effects
- DNA Modification Methylases -- antagonists & inhibitors
- Decitabine
- Gene Expression Regulation, Neoplastic -- drug effects
- HCT116 Cells
- Humans
- Neoplasms -- enzymology
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- RNA Interference
- Time Factors
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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