Improvement of combination chemotherapy tolerance by introduction of polycistronic retroviral vector drug resistance genes MGMT and MDR1 into human umbilical cord blood CD34+ cells. [electronic resource]
Producer: 20020509Description: 281-8 p. digitalISSN:- 0145-2126
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- genetics
- Antigens, CD -- blood
- Antigens, CD34 -- blood
- Antineoplastic Agents -- toxicity
- Carmustine -- toxicity
- DNA, Complementary
- Drug Resistance, Multiple
- Drug Resistance, Neoplasm
- Fetal Blood -- cytology
- Flow Cytometry
- Genes
- Genes, MDR
- Genetic Vectors
- Helper Viruses -- genetics
- Hematopoietic Cell Growth Factors -- pharmacology
- Hematopoietic Stem Cells -- cytology
- Humans
- K562 Cells
- O(6)-Methylguanine-DNA Methyltransferase -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Transfection
- Vincristine -- toxicity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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