A chemical tuned strategy to develop novel irreversible EGFR-TK inhibitors with improved safety and pharmacokinetic profiles. [electronic resource]
Producer: 20150226Description: 9889-900 p. digitalISSN:- 1520-4804
- Animals
- Antineoplastic Agents -- pharmacokinetics
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- drug effects
- ErbB Receptors -- antagonists & inhibitors
- Ether-A-Go-Go Potassium Channels -- metabolism
- Humans
- Lung Neoplasms -- drug therapy
- Mice, Inbred BALB C
- Protein Kinase Inhibitors -- pharmacokinetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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