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Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation. [electronic resource] by
- Koch, Philipp
- Tamboli, Irfan Y
- Mertens, Jerome
- Wunderlich, Patrick
- Ladewig, Julia
- Stüber, Kathrin
- Esselmann, Hermann
- Wiltfang, Jens
- Brüstle, Oliver
- Walter, Jochen
Producer: 20120828
In:
The American journal of pathology vol. 180
Availability: No items available.
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Intramembranous processing by γ-secretase regulates reverse signaling of ephrin-B2 in migration of microglia. [electronic resource] by
- Kemmerling, Nadja
- Wunderlich, Patrick
- Theil, Sandra
- Linnartz-Gerlach, Bettina
- Hersch, Nils
- Hoffmann, Bernd
- Heneka, Michael T
- de Strooper, Bart
- Neumann, Harald
- Walter, Jochen
Producer: 20180307
In:
Glia vol. 65
Availability: No items available.
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Proteolytic processing of the serine protease matriptase-2: identification of the cleavage sites required for its autocatalytic release from the cell surface. [electronic resource] by
- Stirnberg, Marit
- Maurer, Eva
- Horstmeyer, Angelika
- Kolp, Sonja
- Frank, Stefan
- Bald, Tobias
- Arenz, Katharina
- Janzer, Andreas
- Prager, Kai
- Wunderlich, Patrick
- Walter, Jochen
- Gütschow, Michael
Producer: 20100813
In:
The Biochemical journal vol. 430
Availability: No items available.
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Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion. [electronic resource] by
- Tamboli, Irfan Y
- Barth, Esther
- Christian, Leonie
- Siepmann, Martin
- Kumar, Sathish
- Singh, Sandesh
- Tolksdorf, Karen
- Heneka, Michael T
- Lütjohann, Dieter
- Wunderlich, Patrick
- Walter, Jochen
Producer: 20101230
In:
The Journal of biological chemistry vol. 285
Availability: No items available.
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APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation. [electronic resource] by
- Mertens, Jerome
- Stüber, Kathrin
- Wunderlich, Patrick
- Ladewig, Julia
- Kesavan, Jaideep C
- Vandenberghe, Rik
- Vandenbulcke, Mathieu
- van Damme, Philip
- Walter, Jochen
- Brüstle, Oliver
- Koch, Philipp
Producer: 20150511
In:
Stem cell reports vol. 1
Availability: No items available.
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Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity. [electronic resource] by
- Kumar, Sathish
- Wirths, Oliver
- Stüber, Kathrin
- Wunderlich, Patrick
- Koch, Philipp
- Theil, Sandra
- Rezaei-Ghaleh, Nasrollah
- Zweckstetter, Markus
- Bayer, Thomas A
- Brüstle, Oliver
- Thal, Dietmar R
- Walter, Jochen
Producer: 20161213
In:
Acta neuropathologica vol. 131
Availability: No items available.
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