2-(Naphthalene-1-yl)-6-pyrrolidinyl-4-quinazolinone inhibits skin cancer M21 cell proliferation through aberrant expression of microtubules and the cell cycle. [electronic resource]
Producer: 20111031Description: 942-51 p. digitalISSN:- 1521-0103
- Annexin A5 -- metabolism
- Antineoplastic Agents -- pharmacology
- Blotting, Western
- CDC2 Protein Kinase -- metabolism
- Caspases -- metabolism
- Cell Cycle -- drug effects
- Cell Division -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Coloring Agents
- Cyclin B1 -- metabolism
- DNA, Neoplasm -- biosynthesis
- Drug Design
- G2 Phase -- drug effects
- Humans
- Immunohistochemistry
- Microtubules -- drug effects
- Mitosis -- drug effects
- Models, Molecular
- Phosphorylation
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Pyrrolidines -- pharmacology
- Quinazolinones -- pharmacology
- Skin Neoplasms -- drug therapy
- Trypan Blue
- Tubulin
- Tubulin Modulators -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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