Expression of p21(WAF1/Cip1) through Sp1 sites by histone deacetylase inhibitor apicidin requires PI 3-kinase-PKC epsilon signaling pathway. [electronic resource]
Producer: 20031007Description: 6023-31 p. digitalISSN:- 0950-9232
- Acetylation -- drug effects
- Binding Sites
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins -- biosynthesis
- Enzyme Inhibitors -- metabolism
- Gene Expression -- drug effects
- HeLa Cells
- Histone Deacetylase Inhibitors
- Humans
- Peptides, Cyclic -- metabolism
- Phosphatidylinositol 3-Kinases -- drug effects
- Phosphoinositide-3 Kinase Inhibitors
- Plicamycin -- pharmacology
- Promoter Regions, Genetic
- Protein Kinase C -- antagonists & inhibitors
- Protein Kinase C-epsilon
- Signal Transduction -- drug effects
- Sp1 Transcription Factor -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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