Combining mutations that modulate inter-subunit interactions and proteolytic inactivation enhance the stability of factor VIIIa. [electronic resource]
Producer: 20150511Description: 43-52 p. digitalISSN:- 2567-689X
- Factor VIIIa -- genetics
- Factor Xa -- metabolism
- Hemophilia A -- genetics
- Hot Temperature -- adverse effects
- Humans
- Kinetics
- Mutation -- genetics
- Protein Engineering
- Protein Interaction Domains and Motifs -- genetics
- Protein Stability
- Protein Structure, Tertiary
- Protein Subunits -- genetics
- Proteolysis
- Thrombin -- metabolism
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Publication Type: Journal Article
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