Anti-leukemic mechanisms of pegylated arginase I in acute lymphoblastic T-cell leukemia. [electronic resource]
Producer: 20130430Description: 569-77 p. digitalISSN:- 1476-5551
- Animals
- Apoptosis -- drug effects
- Arginase -- administration & dosage
- Blotting, Western
- Cell Proliferation -- drug effects
- Eukaryotic Initiation Factor-2 -- metabolism
- Female
- Fluorescent Antibody Technique
- Humans
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Phosphorylation
- Polyethylene Glycols -- chemistry
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma -- metabolism
- Protein Phosphatase 1 -- metabolism
- Protein Serine-Threonine Kinases -- metabolism
- Recombinant Proteins -- therapeutic use
- Signal Transduction
- Survival Rate
- eIF-2 Kinase -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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