UV light-induced degradation of RNA polymerase II is dependent on the Cockayne's syndrome A and B proteins but not p53 or MLH1. [electronic resource]
Producer: 20010510Description: 93-105 p. digitalISSN:- 0027-5107
- Adaptor Proteins, Signal Transducing
- Animals
- Blotting, Western
- CHO Cells
- Carrier Proteins
- Cell Line
- Cricetinae
- Cysteine Endopeptidases
- DNA Helicases -- genetics
- DNA Repair -- radiation effects
- DNA Repair Enzymes
- Enzyme Inhibitors -- pharmacology
- Fibroblasts -- cytology
- Fluorescent Antibody Technique
- Humans
- Multienzyme Complexes -- antagonists & inhibitors
- MutL Protein Homolog 1
- Neoplasm Proteins -- deficiency
- Nuclear Proteins
- Peptide Hydrolases -- metabolism
- Phosphorylation -- drug effects
- Poly-ADP-Ribose Binding Proteins
- Proteasome Endopeptidase Complex
- Proteins -- genetics
- RNA -- biosynthesis
- RNA Polymerase II -- metabolism
- Transcription Factors
- Transcription, Genetic -- radiation effects
- Tumor Suppressor Protein p53 -- deficiency
- Ultraviolet Rays
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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