Regulation of UDP-glucose dehydrogenase is sufficient to modulate hyaluronan production and release, control sulfated GAG synthesis, and promote chondrogenesis. [electronic resource]
Producer: 20110127Description: 749-61 p. digitalISSN:- 1097-4652
- Animals
- Chickens
- Chondrogenesis -- drug effects
- Chondroitin Sulfates -- metabolism
- Electrophoresis
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Gene Expression Regulation, Enzymologic -- drug effects
- Glycosaminoglycans -- biosynthesis
- Hyaluronic Acid -- biosynthesis
- Joints -- cytology
- MAP Kinase Signaling System -- drug effects
- Mitogen-Activated Protein Kinase Kinases -- metabolism
- Models, Biological
- RNA, Messenger -- genetics
- Transforming Growth Factor beta -- pharmacology
- Uridine Diphosphate Glucose Dehydrogenase -- genetics
- p38 Mitogen-Activated Protein Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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