Rescue of expression and signaling of human luteinizing hormone G protein-coupled receptor mutants with an allosterically binding small-molecule agonist. [electronic resource]
Producer: 20110624Description: 7172-6 p. digitalISSN:- 1091-6490
- Allosteric Regulation -- drug effects
- Amino Acid Substitution
- Cell Membrane -- genetics
- Female
- Fertility Agents -- pharmacology
- Gene Expression Regulation -- drug effects
- Glycosylation -- drug effects
- HEK293 Cells
- Humans
- Infertility -- drug therapy
- Luteinizing Hormone -- pharmacology
- Male
- Mutation, Missense
- Protein Transport -- drug effects
- Receptors, LH -- agonists
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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