The roles of cytochrome P450 3A4 and 1A2 in the 3-hydroxylation of quinine in vivo. [electronic resource]
Producer: 19991206Description: 454-60 p. digitalISSN:- 0009-9236
- Adult
- Antifungal Agents -- pharmacology
- Antimalarials -- metabolism
- Area Under Curve
- Cross-Over Studies
- Cytochrome P-450 CYP1A2 -- metabolism
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- metabolism
- Female
- Fluvoxamine -- pharmacology
- Humans
- Hydroxylation -- drug effects
- Ketoconazole -- pharmacology
- Male
- Mixed Function Oxygenases -- metabolism
- Quinidine -- analogs & derivatives
- Quinine -- metabolism
- Selective Serotonin Reuptake Inhibitors -- pharmacology
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Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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