The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting. [electronic resource]
Producer: 20180511Description: 99 p. digitalISSN:- 1465-542X
- Antineoplastic Combined Chemotherapy Protocols -- adverse effects
- BRCA1 Protein -- genetics
- Biomarkers, Tumor
- Breast Neoplasms -- drug therapy
- Chemotherapy, Adjuvant
- Cluster Analysis
- Female
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic -- drug effects
- Gene Regulatory Networks
- Humans
- Neoadjuvant Therapy
- Poly(ADP-ribose) Polymerase Inhibitors -- administration & dosage
- Sensitivity and Specificity
- Treatment Outcome
- Triple Negative Breast Neoplasms -- drug therapy
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Publication Type: Journal Article
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