Profoundly different prion diseases in knock-in mice carrying single PrP codon substitutions associated with human diseases. [electronic resource]
Producer: 20131216Description: 14759-64 p. digitalISSN:- 1091-6490
- Animals
- Blotting, Western
- Brain -- metabolism
- Codon -- genetics
- Creutzfeldt-Jakob Syndrome -- genetics
- Disease Models, Animal
- Female
- Humans
- Immunohistochemistry
- Insomnia, Fatal Familial -- genetics
- Kaplan-Meier Estimate
- Male
- Mice
- Mice, 129 Strain
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Transgenic
- Models, Genetic
- Mutation
- Phenotype
- Prion Diseases -- genetics
- Prions -- genetics
- Proliferating Cell Nuclear Antigen -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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