Tankyrase inhibition aggravates kidney injury in the absence of CD2AP. [electronic resource]
Producer: 20171023Description: e2302 p. digitalISSN:- 2041-4889
- Adaptor Proteins, Signal Transducing -- deficiency
- Animals
- Cell Line, Transformed
- Cytoskeletal Proteins -- deficiency
- Embryo, Nonmammalian
- Fibronectins -- genetics
- Genes, Lethal
- HEK293 Cells
- Heterocyclic Compounds, 3-Ring -- pharmacology
- Humans
- Lymphoid Enhancer-Binding Factor 1 -- genetics
- Male
- Mice
- Mice, Knockout
- Podocytes -- drug effects
- Poly Adenosine Diphosphate Ribose -- metabolism
- Protein Processing, Post-Translational
- Rats
- Rats, Sprague-Dawley
- Renal Insufficiency -- enzymology
- Serpin E2 -- agonists
- Signal Transduction
- Tankyrases -- antagonists & inhibitors
- Zebrafish
- beta Catenin -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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