Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation. [electronic resource]
Producer: 20030909Description: 7084-92 p. digitalISSN:- 1529-2401
- Age Factors
- Animals
- Apoptosis -- genetics
- Body Weight -- genetics
- Brain -- growth & development
- Cell Count
- Cell Division -- physiology
- Cell Survival -- physiology
- Cells, Cultured
- Cerebellum -- cytology
- Crosses, Genetic
- Enzyme Inhibitors -- pharmacology
- Heterozygote
- In Situ Nick-End Labeling
- Insulin Receptor Substrate Proteins
- Intracellular Signaling Peptides and Proteins
- Mice
- Mice, Knockout
- Neurons -- cytology
- Organ Size -- genetics
- Phosphoproteins -- deficiency
- Phosphorylation
- Receptor, IGF Type 1 -- deficiency
- Signal Transduction -- physiology
- tau Proteins -- metabolism
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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