Inhibition of tumor necrosis factor alpha-mediated NFkappaB activation and leukocyte adhesion, with enhanced endothelial apoptosis, by G protein-linked receptor (TP) ligands. [electronic resource]
Producer: 20030519Description: 11858-66 p. digitalISSN:- 0021-9258
- Antigens, CD -- metabolism
- Antineoplastic Agents -- pharmacology
- Apoptosis -- physiology
- Caspases -- metabolism
- Cell Adhesion -- drug effects
- Cells, Cultured
- Endothelium, Vascular -- cytology
- GTP-Binding Proteins -- metabolism
- Heptanoic Acids -- pharmacology
- Humans
- Interleukin-1 -- pharmacology
- Leukocytes -- cytology
- Ligands
- NF-kappa B -- metabolism
- Receptor Cross-Talk -- drug effects
- Receptors, Cell Surface -- metabolism
- Receptors, Tumor Necrosis Factor -- metabolism
- Receptors, Tumor Necrosis Factor, Type I
- Receptors, Tumor Necrosis Factor, Type II
- Signal Transduction -- drug effects
- Thromboxane A2 -- metabolism
- Tumor Necrosis Factor-alpha -- pharmacology
- Umbilical Veins -- cytology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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