Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model. [electronic resource]
Producer: 20160203Description: 391-403 p. digitalISSN:- 1476-5462
- Animals
- Antigens, CD19 -- genetics
- CD28 Antigens -- genetics
- Cell Line, Tumor
- Cells, Cultured
- Genetic Therapy
- HEK293 Cells
- Humans
- Immunotherapy, Adoptive
- Leukemia -- therapy
- Macrophage Activation
- Macrophages -- immunology
- Mice
- Mice, Inbred NOD
- Receptors, Antigen, T-Cell -- genetics
- Receptors, IgG -- genetics
- Receptors, OX40 -- genetics
- Recombinant Proteins -- genetics
- T-Lymphocytes -- immunology
- Xenograft Model Antitumor Assays
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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