A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis. [electronic resource]
Producer: 20120210Description: R15 p. digitalISSN:- 1478-6362
- Adult
- Arthritis, Rheumatoid -- genetics
- Cell Separation
- Cells, Cultured
- Cross-Sectional Studies
- Female
- Genetic Predisposition to Disease -- genetics
- Genotype
- Humans
- Interleukin-17 -- biosynthesis
- Interleukin-4 -- immunology
- Male
- Middle Aged
- Pilot Projects
- Polymorphism, Single Nucleotide
- Receptors, Interleukin-4 -- genetics
- Signal Transduction -- genetics
- Th17 Cells -- immunology
- Young Adult
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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