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Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH). [electronic resource] by
- Min, Xiaoshan
- Thibault, Stephen T
- Porter, Amy C
- Gustin, Darin J
- Carlson, Timothy J
- Xu, Haoda
- Lindstrom, Michelle
- Xu, Guifen
- Uyeda, Craig
- Ma, Zhihua
- Li, Yihong
- Kayser, Frank
- Walker, Nigel P C
- Wang, Zhulun
Producer: 20110715
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 108
Availability: No items available.
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7.
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The high-resolution crystal structure of human LCAT. [electronic resource] by
- Piper, Derek E
- Romanow, William G
- Gunawardane, Ruwanthi N
- Fordstrom, Preston
- Masterman, Stephanie
- Pan, Oscar
- Thibault, Stephen T
- Zhang, Richard
- Meininger, David
- Schwarz, Margrit
- Wang, Zhulun
- King, Chadwick
- Zhou, Mingyue
- Walker, Nigel P C
Producer: 20160527
In:
Journal of lipid research vol. 56
Availability: No items available.
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8.
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SAR and mode of action of novel non-nucleoside inhibitors of hepatitis C NS5b RNA polymerase. [electronic resource] by
- Powers, Jay P
- Piper, Derek E
- Li, Yang
- Mayorga, Veronica
- Anzola, John
- Chen, James M
- Jaen, Juan C
- Lee, Gary
- Liu, Jinqian
- Peterson, M Greg
- Tonn, George R
- Ye, Qiuping
- Walker, Nigel P C
- Wang, Zhulun
Producer: 20060329
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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9.
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Discovery and optimization of piperidyl benzamide derivatives as a novel class of 11beta-HSD1 inhibitors. [electronic resource] by
- Rew, Yosup
- McMinn, Dustin L
- Wang, Zhulun
- He, Xiao
- Hungate, Randall W
- Jaen, Juan C
- Sudom, Athena
- Sun, Daqing
- Tu, Hua
- Ursu, Stefania
- Villemure, Elisia
- Walker, Nigel P C
- Yan, Xuelei
- Ye, Qiuping
- Powers, Jay P
Producer: 20090820
In:
Bioorganic & medicinal chemistry letters vol. 19
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Identification and optimization of N3,N6-diaryl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamines as a novel class of ACK1 inhibitors. [electronic resource] by
- Kopecky, David J
- Hao, Xiaolin
- Chen, Yi
- Fu, Jiasheng
- Jiao, XianYun
- Jaen, Juan C
- Cardozo, Mario G
- Liu, Jinsong
- Wang, Zhulun
- Walker, Nigel P C
- Wesche, Holger
- Li, Shyun
- Farrelly, Ellyn
- Xiao, Shou-Hua
- Kayser, Frank
Producer: 20090429
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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11.
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Discovery of potent, selective, and orally bioavailable inhibitors of interleukin-1 receptor-associate kinase-4. [electronic resource] by
- Wang, Zhulun
- Sun, Daqing
- Johnstone, Sheree
- Cao, Zhaodan
- Gao, Xiong
- Jaen, Juan C
- Liu, Jingqian
- Lively, Sarah
- Miao, Shichang
- Sudom, Athena
- Tomooka, Craig
- Walker, Nigel P C
- Wright, Matthew
- Yan, Xuelei
- Ye, Qiuping
- Powers, Jay P
Producer: 20161005
In:
Bioorganic & medicinal chemistry letters vol. 25
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12.
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Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma. [electronic resource] by
- Connors, Richard V
- Wang, Zhulun
- Harrison, Martin
- Zhang, Alex
- Wanska, Malgorzata
- Hiscock, Steve
- Fox, Brian
- Dore, Michael
- Labelle, Marc
- Sudom, Athena
- Johnstone, Sheree
- Liu, Jinsong
- Walker, Nigel P C
- Chai, Anne
- Siegler, Karen
- Li, Yang
- Coward, Peter
Producer: 20090901
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
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13.
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Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. [electronic resource] by
- Tu, Hua
- Powers, Jay P
- Liu, Jinsong
- Ursu, Stefania
- Sudom, Athena
- Yan, Xuelei
- Xu, Haoda
- Meininger, David
- Degraffenreid, Michael
- He, Xiao
- Jaen, Juan C
- Sun, Daqing
- Labelle, Marc
- Yamamoto, Hiroshi
- Shan, Bei
- Walker, Nigel P C
- Wang, Zhulun
Producer: 20090130
In:
Bioorganic & medicinal chemistry vol. 16
Availability: No items available.
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14.
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Structure-based design of nonpeptide inhibitors of interleukin-1beta converting enzyme (ICE, caspase-1). [electronic resource] by
- Shahripour, Aurash B
- Plummer, Mark S
- Lunney, Elizabeth A
- Albrecht, Hans P
- Hays, Sheryl J
- Kostlan, Catherine R
- Sawyer, Tomi K
- Walker, Nigel P C
- Brady, Kenneth D
- Allen, Hamish J
- Talanian, Robert V
- Wong, Winnie W
- Humblet, Christine
Producer: 20020312
In:
Bioorganic & medicinal chemistry vol. 10
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15.
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INT131: a selective modulator of PPAR gamma. [electronic resource] by
- Motani, Alykhan
- Wang, Zhulun
- Weiszmann, Jennifer
- McGee, Lawrence R
- Lee, Gary
- Liu, Qingxiang
- Staunton, Jocelyn
- Fang, Zexu
- Fuentes, Helen
- Lindstrom, Michelle
- Liu, Jinsong
- Biermann, Donna H T
- Jaen, Juan
- Walker, Nigel P C
- Learned, R Marc
- Chen, Jin-Long
- Li, Yang
Producer: 20090728
In:
Journal of molecular biology vol. 386
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16.
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Optimization of novel di-substituted cyclohexylbenzamide derivatives as potent 11 beta-HSD1 inhibitors. [electronic resource] by
- McMinn, Dustin L
- Rew, Yosup
- Sudom, Athena
- Caille, Seb
- Degraffenreid, Michael
- He, Xiao
- Hungate, Randall
- Jiang, Ben
- Jaen, Juan
- Julian, Lisa D
- Kaizerman, Jacob
- Novak, Perry
- Sun, Daqing
- Tu, Hua
- Ursu, Stefania
- Walker, Nigel P C
- Yan, Xuelei
- Ye, Qiuping
- Wang, Zhulun
- Powers, Jay P
Producer: 20090828
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
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17.
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Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73. [electronic resource] by
- Beatty, Joel W
- Lindsey, Erick A
- Thomas-Tran, Rhiannon
- Debien, Laurent
- Mandal, Debashis
- Jeffrey, Jenna L
- Tran, Anh T
- Fournier, Jeremy
- Jacob, Steven D
- Yan, Xuelei
- Drew, Samuel L
- Ginn, Elaine
- Chen, Ada
- Pham, Amber T
- Zhao, Sharon
- Jin, Lixia
- Young, Stephen W
- Walker, Nigel P
- Leleti, Manmohan Reddy
- Moschütz, Susanne
- Sträter, Norbert
- Powers, Jay P
- Lawson, Kenneth V
Producer: 20200924
In:
Journal of medicinal chemistry vol. 63
Availability: No items available.
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18.
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A novel series of IKKβ inhibitors part II: description of a potent and pharmacologically active series of analogs. [electronic resource] by
- Cushing, Timothy D
- Baichwal, Vijay
- Berry, Karen
- Billedeau, Roland
- Bordunov, Viola
- Broka, Chris
- Browner, Michelle F
- Cardozo, Mario
- Cheng, Peng
- Clark, David
- Dalrymple, Stacie
- DeGraffenreid, Michael
- Gill, Adrian
- Hao, Xiaolin
- Hawley, Ronald C
- He, Xiao
- Labadie, Sharada S
- Labelle, Marc
- Lehel, Csaba
- Lu, Pu-Ping
- McIntosh, Joel
- Miao, Shichang
- Parast, Camran
- Shin, Youngsook
- Sjogren, Eric B
- Smith, Marie-Louise
- Talamas, Francisco X
- Tonn, George
- Walker, Keith M
- Walker, Nigel P C
- Wesche, Holger
- Whitehead, Chris
- Wright, Matt
- Jaen, Juan C
Producer: 20110414
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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19.
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A novel series of IKKβ inhibitors part I: Initial SAR studies of a HTS hit. [electronic resource] by
- Cushing, Timothy D
- Baichwal, Vijay
- Berry, Karen
- Billedeau, Roland
- Bordunov, Viola
- Broka, Chris
- Cardozo, Mario
- Cheng, Peng
- Clark, David
- Dalrymple, Stacie
- DeGraffenreid, Michael
- Gill, Adrian
- Hao, Xiaolin
- Hawley, Ronald C
- He, Xiao
- Jaen, Juan C
- Labadie, Sharada S
- Labelle, Marc
- Lehel, Csaba
- Lu, Pu-Ping
- McIntosh, Joel
- Miao, Shichang
- Parast, Camran
- Shin, Youngsook
- Sjogren, Eric B
- Smith, Marie-Louise
- Talamas, Francisco X
- Tonn, George
- Walker, Keith M
- Walker, Nigel P C
- Wesche, Holger
- Whitehead, Chris
- Wright, Matt
- Browner, Michelle F
Producer: 20110414
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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20.
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A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. [electronic resource] by
- Chan, Joyce C Y
- Piper, Derek E
- Cao, Qiong
- Liu, Dongming
- King, Chadwick
- Wang, Wei
- Tang, Jie
- Liu, Qiang
- Higbee, Jared
- Xia, Zhen
- Di, Yongmei
- Shetterly, Susan
- Arimura, Ziva
- Salomonis, Heather
- Romanow, William G
- Thibault, Stephen T
- Zhang, Richard
- Cao, Ping
- Yang, Xiao-Ping
- Yu, Timothy
- Lu, Mei
- Retter, Marc W
- Kwon, Gayle
- Henne, Kirk
- Pan, Oscar
- Tsai, Mei-Mei
- Fuchslocher, Bryna
- Yang, Evelyn
- Zhou, Lei
- Lee, Ki Jeong
- Daris, Mark
- Sheng, Jackie
- Wang, Yan
- Shen, Wenyan D
- Yeh, Wen-Chen
- Emery, Maurice
- Walker, Nigel P C
- Shan, Bei
- Schwarz, Margrit
- Jackson, Simon M
Producer: 20090714
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 106
Availability: No items available.
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