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Synthesis and structure-activity relationship of dihydrobenzofuran derivatives as novel human GPR119 agonists. [electronic resource] by
- Ye, Xiang-Yang
- Morales, Christian L
- Wang, Ying
- Rossi, Karen A
- Malmstrom, Sarah E
- Abousleiman, Mojgan
- Sereda, Larisa
- Apedo, Atsu
- Robl, Jeffrey A
- Miller, Keith J
- Krupinski, John
- Wacker, Dean A
Producer: 20150102
In:
Bioorganic & medicinal chemistry letters vol. 24
Availability: No items available.
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6.
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N-Arylalkylpiperidine urea derivatives as CC chemokine receptor-3 (CCR3) antagonists. [electronic resource] by
- Batt, Douglas G
- Houghton, Gregory C
- Roderick, John
- Santella, Joseph B
- Wacker, Dean A
- Welch, Patricia K
- Orlovsky, Yevgeniya I
- Wadman, Eric A
- Trzaskos, James M
- Davies, Paul
- Decicco, Carl P
- Carter, Percy H
Producer: 20050607
In:
Bioorganic & medicinal chemistry letters vol. 15
Availability: No items available.
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7.
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Design, structure-activity relationship, and pharmacokinetic profile of pyrazole-based indoline factor Xa inhibitors. [electronic resource] by
- Varnes, Jeffrey G
- Wacker, Dean A
- Jacobson, Irina C
- Quan, Mimi L
- Ellis, Christopher D
- Rossi, Karen A
- He, Ming Y
- Luettgen, Joseph M
- Knabb, Robert M
- Bai, Steven
- He, Kan
- Lam, Patrick Y S
- Wexler, Ruth R
Producer: 20080303
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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8.
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Structure-activity relationship and pharmacokinetic profile of 5-ketopyrazole factor Xa inhibitors. [electronic resource] by
- Varnes, Jeffrey G
- Wacker, Dean A
- Pinto, Donald J P
- Orwat, Michael J
- Theroff, Jay P
- Wells, Brian
- Galemo, Robert A
- Luettgen, Joseph M
- Knabb, Robert M
- Bai, Steven
- He, Kan
- Lam, Patrick Y S
- Wexler, Ruth R
Producer: 20080527
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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9.
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Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists. [electronic resource] by
- Varnes, Jeffrey G
- Gardner, Daniel S
- Santella, Joseph B
- Duncia, John V
- Estrella, Melissa
- Watson, Paul S
- Clark, Cheryl M
- Ko, Soo S
- Welch, Patricia
- Covington, Maryanne
- Stowell, Nicole
- Wadman, Eric
- Davies, Paul
- Solomon, Kimberley
- Newton, Robert C
- Trainor, George L
- Decicco, Carl P
- Wacker, Dean A
Producer: 20041026
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
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10.
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CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure-activity relationships. [electronic resource] by
- Wacker, Dean A
- Santella, Joseph B
- Gardner, Daniel S
- Varnes, Jeffrey G
- Estrella, Melissa
- DeLucca, George V
- Ko, Soo S
- Tanabe, Keiichi
- Watson, Paul S
- Welch, Patricia K
- Covington, Maryanne
- Stowell, Nicole C
- Wadman, Eric A
- Davies, Paul
- Solomon, Kimberly A
- Newton, Robert C
- Trainor, George L
- Friedman, Steven M
- Decicco, Carl P
- Duncia, John V
Producer: 20021119
In:
Bioorganic & medicinal chemistry letters vol. 12
Availability: No items available.
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11.
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Discovery of (R)-9-ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1-a]isoindol- 6(2H)-one, a selective, orally active agonist of the 5-HT(2C) receptor. [electronic resource] by
- Wacker, Dean A
- Varnes, Jeffrey G
- Malmstrom, Sarah E
- Cao, Xueying
- Hung, Chen-Pin
- Ung, Thao
- Wu, Ginger
- Zhang, Ge
- Zuvich, Eva
- Thomas, Michael A
- Keim, William J
- Cullen, Mary Jane
- Rohrbach, Kenneth W
- Qu, Qinling
- Narayanan, Rangaraj
- Rossi, Karen
- Janovitz, Evan
- Lehman-McKeeman, Lois
- Malley, Mary F
- Devenny, James
- Pelleymounter, Mary Ann
- Miller, Keith J
- Robl, Jeffrey A
Producer: 20070427
In:
Journal of medicinal chemistry vol. 50
Availability: No items available.
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12.
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From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part I: the discovery of CCR3 antagonist development candidate BMS-639623 with picomolar inhibition potency against eosinophil chemotaxis. [electronic resource] by
- Santella, Joseph B
- Gardner, Daniel S
- Yao, Wenqing
- Shi, Chongsheng
- Reddy, Prabhakar
- Tebben, Andrew J
- DeLucca, George V
- Wacker, Dean A
- Watson, Paul S
- Welch, Patricia K
- Wadman, Eric A
- Davies, Paul
- Solomon, Kimberly A
- Graden, Dani M
- Yeleswaram, Swamy
- Mandlekar, Sandhya
- Kariv, Ilona
- Decicco, Carl P
- Ko, Soo S
- Carter, Percy H
- Duncia, John V
Producer: 20080527
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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13.
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Utilization of an Active Site Mutant Receptor for the Identification of Potent and Selective Atypical 5-HT [electronic resource] by
- Carpenter, Joseph
- Wang, Ying
- Wu, Gang
- Feng, Jianxin
- Ye, Xiang-Yang
- Morales, Christian L
- Broekema, Matthias
- Rossi, Karen A
- Miller, Keith J
- Murphy, Brian J
- Wu, Ginger
- Malmstrom, Sarah E
- Azzara, Anthony V
- Sher, Philip M
- Fevig, John M
- Alt, Andrew
- Bertekap, Robert L
- Cullen, Mary Jane
- Harper, Timothy M
- Foster, Kimberly
- Luk, Emily
- Xiang, Qian
- Grubb, Mary F
- Robl, Jeffrey A
- Wacker, Dean A
Producer: 20170905
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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14.
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Discovery of CC chemokine receptor-3 (CCR3) antagonists with picomolar potency. [electronic resource] by
- De Lucca, George V
- Kim, Ui Tae
- Vargo, Brian J
- Duncia, John V
- Santella, Joseph B
- Gardner, Daniel S
- Zheng, Changsheng
- Liauw, Ann
- Wang, Zhang
- Emmett, George
- Wacker, Dean A
- Welch, Patricia K
- Covington, Maryanne
- Stowell, Nicole C
- Wadman, Eric A
- Das, Anuk M
- Davies, Paul
- Yeleswaram, Swamy
- Graden, Danielle M
- Solomon, Kimberly A
- Newton, Robert C
- Trainor, George L
- Decicco, Carl P
- Ko, Soo S
Producer: 20050503
In:
Journal of medicinal chemistry vol. 48
Availability: No items available.
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15.
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CC chemokine receptor-3 (CCR3) antagonists: improving the selectivity of DPC168 by reducing central ring lipophilicity. [electronic resource] by
- Pruitt, James R
- Batt, Douglas G
- Wacker, Dean A
- Bostrom, Lori L
- Booker, Shon K
- McLaughlin, Erin
- Houghton, Gregory C
- Varnes, Jeffrey G
- Christ, David D
- Covington, Maryanne
- Das, Anuk M
- Davies, Paul
- Graden, Danielle
- Kariv, Ilona
- Orlovsky, Yevgeniya
- Stowell, Nicole C
- Vaddi, Krishna G
- Wadman, Eric A
- Welch, Patricia K
- Yeleswaram, Swamy
- Solomon, Kimberly A
- Newton, Robert C
- Decicco, Carl P
- Carter, Percy H
- Ko, Soo S
Producer: 20070807
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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16.
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Discovery of 5-chloro-4-((1-(5-chloropyrimidin-2-yl)piperidin-4-yl)oxy)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyridin-2(1H)-one (BMS-903452), an antidiabetic clinical candidate targeting GPR119. [electronic resource] by
- Wacker, Dean A
- Wang, Ying
- Broekema, Matthias
- Rossi, Karen
- O'Connor, Steven
- Hong, Zhenqiu
- Wu, Ginger
- Malmstrom, Sarah E
- Hung, Chen-Pin
- LaMarre, Linda
- Chimalakonda, Anjaneya
- Zhang, Lisa
- Xin, Li
- Cai, Hong
- Chu, Cuixia
- Boehm, Stephanie
- Zalaznick, Jacob
- Ponticiello, Randolph
- Sereda, Larisa
- Han, Song-Ping
- Zebo, Rachel
- Zinker, Bradley
- Luk, Chiuwa Emily
- Wong, Richard
- Everlof, Gerry
- Li, Yi-Xin
- Wu, Chunyu K
- Lee, Michelle
- Griffen, Steven
- Miller, Keith J
- Krupinski, John
- Robl, Jeffrey A
Producer: 20141203
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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