Small-molecule intramimics of formin autoinhibition: a new strategy to target the cytoskeletal remodeling machinery in cancer cells. [electronic resource]
Producer: 20140123Description: 6793-803 p. digitalISSN:- 1538-7445
- Adaptor Proteins, Signal Transducing -- antagonists & inhibitors
- Animals
- Antineoplastic Agents -- pharmacology
- Cytoskeleton -- drug effects
- Feedback, Physiological -- drug effects
- Female
- Formins
- Mice
- Mice, Nude
- Microfilament Proteins -- antagonists & inhibitors
- Molecular Mimicry
- Molecular Targeted Therapy
- NIH 3T3 Cells
- Neoplasms -- drug therapy
- Small Molecule Libraries -- chemistry
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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