The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype. [electronic resource]
Producer: 20130918Description: 2573-83 p. digitalISSN:- 1530-6860
- Arachidonate 12-Lipoxygenase -- metabolism
- Arachidonic Acid -- chemistry
- Biocatalysis -- drug effects
- Cells, Cultured
- Docosahexaenoic Acids -- chemistry
- Epoxide Hydrolases -- metabolism
- Humans
- Leukotriene B4 -- biosynthesis
- Macrophages -- drug effects
- Magnetic Resonance Spectroscopy
- Models, Chemical
- Molecular Structure
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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