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Inhibition of the phosphatidylinositol 3-kinase-Akt pathway enhances gamma-2 herpesvirus lytic replication and facilitates reactivation from latency. [electronic resource] by
- Peng, Li
- Wu, Ting-Ting
- Tchieu, Jason H
- Feng, Jun
- Brown, Helen J
- Feng, Jiaying
- Li, Xudong
- Qi, Jing
- Deng, Hongyu
- Vivanco, Igor
- Mellinghoff, Ingo K
- Jamieson, Christina
- Sun, Ren
Producer: 20100209
In:
The Journal of general virology vol. 91
Availability: No items available.
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11.
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Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer. [electronic resource] by
- Regales, Lucia
- Gong, Yixuan
- Shen, Ronglai
- de Stanchina, Elisa
- Vivanco, Igor
- Goel, Aviva
- Koutcher, Jason A
- Spassova, Maria
- Ouerfelli, Ouathek
- Mellinghoff, Ingo K
- Zakowski, Maureen F
- Politi, Katerina A
- Pao, William
Producer: 20100209
In:
The Journal of clinical investigation vol. 119
Availability: No items available.
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12.
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Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells. [electronic resource] by
- Wang, Maria Y
- Lu, Kan V
- Zhu, Shaojun
- Dia, Ederlyn Q
- Vivanco, Igor
- Shackleford, Gregory M
- Cavenee, Webster K
- Mellinghoff, Ingo K
- Cloughesy, Timothy F
- Sawyers, Charles L
- Mischel, Paul S
Producer: 20071113
In:
Cancer research vol. 66
Availability: No items available.
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Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death. [electronic resource] by
- Graham, Nicholas A
- Tahmasian, Martik
- Kohli, Bitika
- Komisopoulou, Evangelia
- Zhu, Maggie
- Vivanco, Igor
- Teitell, Michael A
- Wu, Hong
- Ribas, Antoni
- Lo, Roger S
- Mellinghoff, Ingo K
- Mischel, Paul S
- Graeber, Thomas G
Producer: 20121130
In:
Molecular systems biology vol. 8
Availability: No items available.
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Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN. [electronic resource] by
- Vivanco, Igor
- Palaskas, Nicolaos
- Tran, Chris
- Finn, Stephen P
- Getz, Gad
- Kennedy, Norman J
- Jiao, Jing
- Rose, Joshua
- Xie, Wanling
- Loda, Massimo
- Golub, Todd
- Mellinghoff, Ingo K
- Davis, Roger J
- Wu, Hong
- Sawyers, Charles L
Producer: 20070712
In:
Cancer cell vol. 11
Availability: No items available.
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15.
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EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer. [electronic resource] by
- Oldrini, Barbara
- Hsieh, Wan-Ying
- Erdjument-Bromage, Hediye
- Codega, Paolo
- Carro, Maria Stella
- Curiel-García, Alvaro
- Campos, Carl
- Pourmaleki, Maryam
- Grommes, Christian
- Vivanco, Igor
- Rohle, Daniel
- Bielski, Craig M
- Taylor, Barry S
- Hollmann, Travis J
- Rosenblum, Marc
- Tempst, Paul
- Blenis, John
- Squatrito, Massimo
- Mellinghoff, Ingo K
Producer: 20181015
In:
Nature communications vol. 8
Availability: No items available.
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16.
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Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies. [electronic resource] by
- Veeriah, Selvaraju
- Taylor, Barry S
- Meng, Shasha
- Fang, Fang
- Yilmaz, Emrullah
- Vivanco, Igor
- Janakiraman, Manickam
- Schultz, Nikolaus
- Hanrahan, Aphrothiti J
- Pao, William
- Ladanyi, Marc
- Sander, Chris
- Heguy, Adriana
- Holland, Eric C
- Paty, Philip B
- Mischel, Paul S
- Liau, Linda
- Cloughesy, Timothy F
- Mellinghoff, Ingo K
- Solit, David B
- Chan, Timothy A
Producer: 20100212
In:
Nature genetics vol. 42
Availability: No items available.
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The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation. [electronic resource] by
- Vivanco, Igor
- Rohle, Daniel
- Versele, Matthias
- Iwanami, Akio
- Kuga, Daisuke
- Oldrini, Barbara
- Tanaka, Kazuhiro
- Dang, Julie
- Kubek, Sara
- Palaskas, Nicolaos
- Hsueh, Teli
- Evans, Michael
- Mulholland, David
- Wolle, Daniel
- Rajasekaran, Sigrid
- Rajasekaran, Ayyappan
- Liau, Linda M
- Cloughesy, Timothy F
- Dikic, Ivan
- Brennan, Cameron
- Wu, Hong
- Mischel, Paul S
- Perera, Timothy
- Mellinghoff, Ingo K
Producer: 20100505
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 107
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18.
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The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers. [electronic resource] by
- Veeriah, Selvaraju
- Brennan, Cameron
- Meng, Shasha
- Singh, Bhuvanesh
- Fagin, James A
- Solit, David B
- Paty, Philip B
- Rohle, Dan
- Vivanco, Igor
- Chmielecki, Juliann
- Pao, William
- Ladanyi, Marc
- Gerald, William L
- Liau, Linda
- Cloughesy, Timothy C
- Mischel, Paul S
- Sander, Chris
- Taylor, Barry
- Schultz, Nikolaus
- Major, John
- Heguy, Adriana
- Fang, Fang
- Mellinghoff, Ingo K
- Chan, Timothy A
Producer: 20090706
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 106
Availability: No items available.
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19.
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Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. [electronic resource] by
- Mellinghoff, Ingo K
- Wang, Maria Y
- Vivanco, Igor
- Haas-Kogan, Daphne A
- Zhu, Shaojun
- Dia, Ederlyn Q
- Lu, Kan V
- Yoshimoto, Koji
- Huang, Julie H Y
- Chute, Dennis J
- Riggs, Bridget L
- Horvath, Steve
- Liau, Linda M
- Cavenee, Webster K
- Rao, P Nagesh
- Beroukhim, Rameen
- Peck, Timothy C
- Lee, Jeffrey C
- Sellers, William R
- Stokoe, David
- Prados, Michael
- Cloughesy, Timothy F
- Sawyers, Charles L
- Mischel, Paul S
Producer: 20051122
In:
The New England journal of medicine vol. 353
Availability: No items available.
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20.
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Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. [electronic resource] by
- Beroukhim, Rameen
- Getz, Gad
- Nghiemphu, Leia
- Barretina, Jordi
- Hsueh, Teli
- Linhart, David
- Vivanco, Igor
- Lee, Jeffrey C
- Huang, Julie H
- Alexander, Sethu
- Du, Jinyan
- Kau, Tweeny
- Thomas, Roman K
- Shah, Kinjal
- Soto, Horacio
- Perner, Sven
- Prensner, John
- Debiasi, Ralph M
- Demichelis, Francesca
- Hatton, Charlie
- Rubin, Mark A
- Garraway, Levi A
- Nelson, Stan F
- Liau, Linda
- Mischel, Paul S
- Cloughesy, Tim F
- Meyerson, Matthew
- Golub, Todd A
- Lander, Eric S
- Mellinghoff, Ingo K
- Sellers, William R
Producer: 20080111
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 104
Availability: No items available.
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