The anti-proliferative effect of neurokinin-A on hematopoietic progenitor cells is partly mediated by p53 activating the 5' flanking region of neurokinin-2 receptor. [electronic resource]
Producer: 20060418Description: 422-32 p. digitalISSN:- 0898-6568
- 5' Flanking Region -- physiology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Electrophoretic Mobility Shift Assay
- Gene Expression Regulation -- drug effects
- Granulocyte-Macrophage Colony-Stimulating Factor -- pharmacology
- Hematopoietic Stem Cells -- drug effects
- Humans
- K562 Cells
- Neurokinin A -- genetics
- RNA, Messenger -- genetics
- Receptors, Neurokinin-2 -- drug effects
- Signal Transduction -- drug effects
- Substance P -- pharmacology
- Tumor Suppressor Protein p53 -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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