Mutant huntingtin activates Nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease. [electronic resource]
Producer: 20090113Description: 84 p. digitalISSN:- 1471-2199
- Animals
- Disease Models, Animal
- Dopamine -- biosynthesis
- Green Fluorescent Proteins -- genetics
- Huntingtin Protein
- Huntington Disease -- genetics
- Mutation
- NF-E2-Related Factor 2 -- genetics
- Nerve Tissue Proteins -- genetics
- Nuclear Proteins -- genetics
- Oxidative Stress
- PC12 Cells
- RNA, Messenger -- metabolism
- Rats
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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