Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo. [electronic resource]
Producer: 20160412Description: 3618-31 p. digitalISSN:- 1742-4658
- Alzheimer Disease -- genetics
- Amyloid Precursor Protein Secretases -- antagonists & inhibitors
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Aspartic Acid Endopeptidases -- antagonists & inhibitors
- Camelids, New World -- immunology
- Cell Line
- Disease Models, Animal
- Disease Progression
- Female
- Humans
- Immunoglobulin Fragments -- administration & dosage
- Immunoglobulin Heavy Chains -- administration & dosage
- In Vitro Techniques
- Mice
- Mice, Transgenic
- Recombinant Proteins -- genetics
- Vaccination
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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