The programmed death 1/programmed death ligand 1 inhibitory pathway is up-regulated in rheumatoid synovium and regulates peripheral T cell responses in human and murine arthritis. [electronic resource]
Producer: 20100729Description: 1870-80 p. digitalISSN:- 1529-0131
- Aged
- Animals
- Antigens, CD -- metabolism
- Antigens, Surface -- metabolism
- Apoptosis Regulatory Proteins -- metabolism
- Arthritis, Experimental -- metabolism
- Arthritis, Rheumatoid -- metabolism
- B7-1 Antigen -- metabolism
- B7-H1 Antigen
- Female
- Flow Cytometry
- Humans
- Interferon-gamma -- metabolism
- Lymphocyte Activation
- Male
- Membrane Glycoproteins -- deficiency
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Middle Aged
- Osteoarthritis -- metabolism
- Peptides -- deficiency
- Programmed Cell Death 1 Receptor
- Recombinant Proteins -- pharmacology
- Synovial Membrane -- metabolism
- T-Lymphocytes -- immunology
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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