Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease. [electronic resource]
Producer: 20170926Description: 46-52 p. digitalISSN:- 1873-2399
- Anemia, Sickle Cell -- metabolism
- Animals
- Disease Models, Animal
- Erythrocytes -- drug effects
- Histone Demethylases -- metabolism
- Humans
- Mice
- Mitochondria -- drug effects
- Models, Biological
- Reactive Oxygen Species -- metabolism
- Rhodamines -- pharmacology
- Sirolimus -- pharmacology
- Spiro Compounds -- pharmacology
- TOR Serine-Threonine Kinases -- metabolism
- Thiophenes -- pharmacology
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Publication Type: Journal Article
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