The emergence of YMDD mutants precedes biochemical flare by 19 weeks in lamivudine-treated chronic hepatitis B patients: an opportunity for therapy reevaluation. [electronic resource]
Producer: 20081008Description: 1605-14 p. digitalISSN:- 1414-431X
- Adult
- Aged
- Alanine Transaminase -- blood
- Amino Acid Motifs -- genetics
- DNA, Viral -- blood
- Drug Resistance, Viral -- genetics
- Female
- Follow-Up Studies
- Hepatitis B e Antigens -- blood
- Hepatitis B virus -- drug effects
- Hepatitis B, Chronic -- drug therapy
- Humans
- Lamivudine -- therapeutic use
- Male
- Middle Aged
- Mutation -- genetics
- Polymerase Chain Reaction
- Prospective Studies
- Reverse Transcriptase Inhibitors -- therapeutic use
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Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
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