Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site. [electronic resource]
Producer: 19930525Description: 4185-94 p. digitalISSN:- 0006-2960
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- Affinity Labels
- Amino Acid Sequence
- Animals
- Azides -- metabolism
- Binding Sites
- Biological Transport
- CHO Cells
- Cell Membrane -- metabolism
- Cloning, Molecular
- Colchicine -- metabolism
- Cricetinae
- Dactinomycin -- metabolism
- Doxorubicin
- Drug Resistance -- genetics
- Gramicidin -- metabolism
- Iodine Radioisotopes
- Kinetics
- Membrane Glycoproteins -- genetics
- Mice
- Mutagenesis, Site-Directed
- Phenylalanine
- Prazosin -- analogs & derivatives
- Serine
- Transfection
- Vinblastine -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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