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Continuous RANKL inhibition in osteoprotegerin transgenic mice and rats suppresses bone resorption without impairing lymphorganogenesis or functional immune responses. [electronic resource] by
- Stolina, Marina
- Dwyer, Denise
- Ominsky, Michael S
- Corbin, Timothy
- Van, Gwyneth
- Bolon, Brad
- Sarosi, Ildiko
- McCabe, James
- Zack, Debra J
- Kostenuik, Paul
Producer: 20080205
In:
Journal of immunology (Baltimore, Md. : 1950) vol. 179
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Anti-Epo receptor antibodies do not predict Epo receptor expression. [electronic resource] by
- Elliott, Steve
- Busse, Leigh
- Bass, Michael B
- Lu, Hsieng
- Sarosi, Ildiko
- Sinclair, Angus M
- Spahr, Chris
- Um, Moonkyoung
- Van, Gwyneth
- Begley, C Glenn
Producer: 20060403
In:
Blood vol. 107
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7.
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RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFalpha or anti-IL-1 therapies. [electronic resource] by
- Stolina, Marina
- Schett, Georg
- Dwyer, Denise
- Vonderfecht, Steven
- Middleton, Scot
- Duryea, Diane
- Pacheco, Efrain
- Van, Gwyneth
- Bolon, Brad
- Feige, Ulrich
- Zack, Debra
- Kostenuik, Paul
Producer: 20100520
In:
Arthritis research & therapy vol. 11
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8.
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Inhibition of interleukin-1 but not tumor necrosis factor suppresses neovascularization in rat models of corneal angiogenesis and adjuvant arthritis. [electronic resource] by
- Coxon, Angela
- Bolon, Brad
- Estrada, Juan
- Kaufman, Stephen
- Scully, Sheila
- Rattan, Alana
- Duryea, Diane
- Hu, Yi-Ling
- Rex, Karen
- Pacheco, Efrain
- Van, Gwyneth
- Zack, Debra
- Feige, Ulrich
Producer: 20021114
In:
Arthritis and rheumatism vol. 46
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Regulatory effects of novel neurotrophin-1/b cell-stimulating factor-3 (cardiotrophin-like cytokine) on B cell function. [electronic resource] by
- Senaldi, Giorgio
- Stolina, Marina
- Guo, Jane
- Faggioni, Raffaella
- McCabe, Susan
- Kaufman, Stephen A
- Van, Gwyneth
- Xu, Weilong
- Fletcher, Frederick A
- Boone, Thomas
- Chang, Ming-Shi
- Sarmiento, Ulla
- Cattley, Russell C
Producer: 20020612
In:
Journal of immunology (Baltimore, Md. : 1950) vol. 168
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A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage. [electronic resource] by
- Nakayama, Naoki
- Han, Chun-ya E
- Cam, Linh
- Lee, Jae I
- Pretorius, Jim
- Fisher, Seth
- Rosenfeld, Robert
- Scully, Sheila
- Nishinakamura, Ryuichi
- Duryea, Diane
- Van, Gwyneth
- Bolon, Brad
- Yokota, Takashi
- Zhang, Ke
Producer: 20040303
In:
Development (Cambridge, England) vol. 131
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11.
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Antagonism of Ang-Tie2 and Dll4-Notch signaling has opposing effects on tumor endothelial cell proliferation, evidenced by a new flow cytometry method. [electronic resource] by
- Payton, Marc
- Jun, Toni
- Wayne, William
- Yu, Dongyin
- Manoukian, Raffi
- Chung, Grace
- Zhang, Nancy
- Sun, Ji-Rong
- Kaplan-Lefko, Paula
- Scully, Sheila
- Van, Gwyneth
- Radinsky, Robert
- Kendall, Richard
- Oliner, Jonathan
- Coxon, Angela
Producer: 20141230
In:
Laboratory investigation; a journal of technical methods and pathology vol. 94
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12.
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Differential temporal effects of sclerostin antibody and parathyroid hormone on cancellous and cortical bone and quantitative differences in effects on the osteoblast lineage in young intact rats. [electronic resource] by
- Ominsky, Michael S
- Brown, Danielle L
- Van, Gwyneth
- Cordover, David
- Pacheco, Efrain
- Frazier, Emily
- Cherepow, Linda
- Higgins-Garn, Marnie
- Aguirre, J Ignacio
- Wronski, Thomas J
- Stolina, Marina
- Zhou, Lei
- Pyrah, Ian
- Boyce, Rogely Waite
Producer: 20161005
In:
Bone vol. 81
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Potent activity of soluble B7RP-1-Fc in therapy of murine tumors in syngeneic hosts. [electronic resource] by
- Ara, Gulshan
- Baher, Angelo
- Storm, Neal
- Horan, Tom
- Baikalov, Claudia
- Brisan, Emil
- Camacho, Reuben
- Moore, Alison
- Goldman, Hartt
- Kohno, Tadahiko
- Cattley, Russell C
- Van, Gwyneth
- Gaida, Kevin
- Zhang, Ming
- Whoriskey, John S
- Fong, David
- Yoshinaga, Steven K
Producer: 20030220
In:
International journal of cancer vol. 103
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Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production. [electronic resource] by
- Kim, Mee Rhan
- Manoukian, Raffi
- Yeh, Richard
- Silbiger, Scott M
- Danilenko, Dimitry M
- Scully, Sheila
- Sun, Jilin
- DeRose, Margaret L
- Stolina, Marina
- Chang, David
- Van, Gwyneth Y
- Clarkin, Kristie
- Nguyen, Hung Q
- Yu, Yan Bin
- Jing, Shuqian
- Senaldi, Giorgio
- Elliott, Gary
- Medlock, Eugene S
Producer: 20021205
In:
Blood vol. 100
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Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 5. A Novel Aryl Sulfone Series, Optimization Through Conformational Analysis. [electronic resource] by
- Tamayo, Nuria A
- Norman, Mark H
- Bartberger, Michael D
- Hong, Fang-Tsao
- Bo, Yunxin
- Liu, Longbin
- Nishimura, Nobuko
- Yang, Kevin C
- Tadesse, Seifu
- Fotsch, Christopher
- Chen, Jie
- Chmait, Samer
- Cupples, Rod
- Hale, Clarence
- Jordan, Steven R
- Lloyd, David J
- Sivits, Glenn
- Van, Gwyneth
- St Jean, David J
Producer: 20150928
In:
Journal of medicinal chemistry vol. 58
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The candidate neuroprotective agent artemin induces autonomic neural dysplasia without preventing peripheral nerve dysfunction. [electronic resource] by
- Bolon, Brad
- Jing, Shuqian
- Asuncion, Frank
- Scully, Sheila
- Pisegna, Marlese
- Van, Gwyneth Y
- Hu, Zheng
- Yu, Yan Bin
- Min, Hosung
- Wild, Ken
- Rosenfeld, Robert D
- Tarpley, John
- Carnahan, Josette
- Duryea, Diane
- Hill, Dave
- Kaufman, Steve
- Yan, Xiao-Qiang
- Juan, Todd
- Christensen, Kathy
- McCabe, James
- Simonet, W Scott
Producer: 20050131
In:
Toxicologic pathology vol. 32
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Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock-in mice that express chimeric (murine/human) RANKL. [electronic resource] by
- Kostenuik, Paul J
- Nguyen, Hung Q
- McCabe, James
- Warmington, Kelly S
- Kurahara, Carol
- Sun, Ning
- Chen, Ching
- Li, Luke
- Cattley, Russ C
- Van, Gwyneth
- Scully, Shelia
- Elliott, Robin
- Grisanti, Mario
- Morony, Sean
- Tan, Hong Lin
- Asuncion, Frank
- Li, Xiaodong
- Ominsky, Michael S
- Stolina, Marina
- Dwyer, Denise
- Dougall, William C
- Hawkins, Nessa
- Boyle, William J
- Simonet, William S
- Sullivan, John K
Producer: 20090828
In:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research vol. 24
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18.
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Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. Discovery of a novel tool compound for in vivo proof-of-concept. [electronic resource] by
- Ashton, Kate S
- Andrews, Kristin L
- Bryan, Marian C
- Bryan, Marion C
- Chen, Jie
- Chen, Kui
- Chen, Michelle
- Chmait, Samer
- Croghan, Michael
- Cupples, Rod
- Fotsch, Christopher
- Helmering, Joan
- Jordan, Steve R
- Kurzeja, Robert J M
- Michelsen, Klaus
- Pennington, Lewis D
- Poon, Steve F
- Sivits, Glenn
- Van, Gwyneth
- Vonderfecht, Steve L
- Wahl, Robert C
- Zhang, Jiandong
- Lloyd, David J
- Hale, Clarence
- St Jean, David J
Producer: 20140401
In:
Journal of medicinal chemistry vol. 57
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19.
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Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profiles. [electronic resource] by
- St Jean, David J
- Ashton, Kate S
- Bartberger, Michael D
- Chen, Jie
- Chmait, Samer
- Cupples, Rod
- Galbreath, Elizabeth
- Helmering, Joan
- Hong, Fang-Tsao
- Jordan, Steven R
- Liu, Longbin
- Kunz, Roxanne K
- Michelsen, Klaus
- Nishimura, Nobuko
- Pennington, Lewis D
- Poon, Steve F
- Reid, Darren
- Sivits, Glenn
- Stec, Markian M
- Tadesse, Seifu
- Tamayo, Nuria
- Van, Gwyneth
- Yang, Kevin C
- Zhang, Jiandong
- Norman, Mark H
- Fotsch, Christopher
- Lloyd, David J
- Hale, Clarence
Producer: 20140401
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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20.
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Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors. [electronic resource] by
- Lloyd, David J
- St Jean, David J
- Kurzeja, Robert J M
- Wahl, Robert C
- Michelsen, Klaus
- Cupples, Rod
- Chen, Michelle
- Wu, John
- Sivits, Glenn
- Helmering, Joan
- Komorowski, Renée
- Ashton, Kate S
- Pennington, Lewis D
- Fotsch, Christopher
- Vazir, Mukta
- Chen, Kui
- Chmait, Samer
- Zhang, Jiandong
- Liu, Longbin
- Norman, Mark H
- Andrews, Kristin L
- Bartberger, Michael D
- Van, Gwyneth
- Galbreath, Elizabeth J
- Vonderfecht, Steven L
- Wang, Minghan
- Jordan, Steven R
- Véniant, Murielle M
- Hale, Clarence
Producer: 20140121
In:
Nature vol. 504
Availability: No items available.
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