Aloe emodin inhibits colon cancer cell migration/angiogenesis by downregulating MMP-2/9, RhoB and VEGF via reduced DNA binding activity of NF-κB. [electronic resource]
Producer: 20120910Description: 581-91 p. digitalISSN:- 1879-0720
- Angiogenesis Inhibitors -- pharmacology
- Anthraquinones -- pharmacology
- Cell Movement -- drug effects
- Cell Nucleus -- drug effects
- Colonic Neoplasms -- drug therapy
- DNA -- genetics
- Down-Regulation -- drug effects
- Endothelial Cells -- drug effects
- Gene Expression Regulation, Neoplastic
- Humans
- MAP Kinase Signaling System -- drug effects
- Matrix Metalloproteinase 2 -- genetics
- Matrix Metalloproteinase 9 -- genetics
- Matrix Metalloproteinase Inhibitors
- NF-kappa B -- antagonists & inhibitors
- Neoplasm Invasiveness
- Neovascularization, Pathologic -- drug therapy
- Phosphorylation -- drug effects
- Promoter Regions, Genetic
- Protein Transport -- drug effects
- RNA, Messenger -- genetics
- Signal Transduction -- drug effects
- Tumor Cells, Cultured
- Vascular Endothelial Growth Factor A -- antagonists & inhibitors
- rhoB GTP-Binding Protein -- antagonists & inhibitors
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.