Chemical rescue of I-site cleavage in living cells and in vitro discriminates between the cytomegalovirus protease, assemblin, and its precursor, pUL80a. [electronic resource]
Producer: 20051130Description: 33206-12 p. digitalISSN:- 0021-9258
- Alanine -- metabolism
- Amino Acid Substitution
- Cell Line
- Cell Line, Transformed
- Cell Transformation, Viral
- Cloning, Molecular
- Cytomegalovirus -- enzymology
- Enzyme Inhibitors -- pharmacology
- Enzyme Precursors -- genetics
- Feasibility Studies
- Glycine -- metabolism
- Humans
- Imidazoles -- pharmacology
- Kinetics
- Mutagenesis, Site-Directed
- Plasmids
- Sequence Analysis, Protein
- Serine Endopeptidases -- chemistry
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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