Discovery of certain benzyl/phenethyl thiazolidinone-indole hybrids as potential anti-proliferative agents: Synthesis, molecular modeling and tubulin polymerization inhibition study. [electronic resource]
Producer: 20201022Description: 103188 p. digitalISSN:- 1090-2120
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Benzene -- chemistry
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Drug Screening Assays, Antitumor
- Humans
- Hydrogen Bonding
- Hydrophobic and Hydrophilic Interactions
- Indoles -- chemical synthesis
- Membrane Potential, Mitochondrial -- drug effects
- Molecular Docking Simulation
- Molecular Structure
- Protein Binding
- Static Electricity
- Structure-Activity Relationship
- Thiazolidines -- chemistry
- Tubulin -- metabolism
- Tubulin Modulators -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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