Long-term treatment of bile duct-ligated rats with rapamycin (sirolimus) significantly attenuates liver fibrosis: analysis of the underlying mechanisms. [electronic resource]
Producer: 20050714Description: 952-61 p. digitalISSN:- 0022-3565
- Animals
- Bile Ducts -- pathology
- Cell Cycle Proteins -- analysis
- Cell Proliferation -- drug effects
- Connective Tissue Growth Factor
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclin-Dependent Kinase Inhibitor p27
- Immediate-Early Proteins -- genetics
- Intercellular Signaling Peptides and Proteins -- genetics
- Ligation
- Liver Cirrhosis, Experimental -- metabolism
- Male
- Phosphorylation
- Rats
- Rats, Wistar
- Sirolimus -- therapeutic use
- Transforming Growth Factor beta -- genetics
- Transforming Growth Factor beta1
- Tumor Suppressor Proteins -- analysis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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