Identification and validation of novel small molecule disruptors of HuR-mRNA interaction. [electronic resource]
Producer: 20160310Description: 1476-84 p. digitalISSN:- 1554-8937
- Binding Sites -- drug effects
- Cell Line
- Cell Survival -- drug effects
- ELAV-Like Protein 1 -- antagonists & inhibitors
- Epithelial Cells -- cytology
- Fibroblasts -- cytology
- Gene Expression Regulation
- Genes, Reporter
- HCT116 Cells
- High-Throughput Screening Assays
- Humans
- Immunoprecipitation
- Luciferases -- genetics
- Molecular Probes -- chemistry
- Nerve Tissue Proteins -- antagonists & inhibitors
- Protein Binding -- drug effects
- RNA, Messenger -- antagonists & inhibitors
- RNA-Binding Proteins -- antagonists & inhibitors
- Response Elements -- drug effects
- Signal Transduction
- Small Molecule Libraries -- chemistry
- Surface Plasmon Resonance
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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