HIF1α Suppresses Tumor Cell Proliferation through Inhibition of Aspartate Biosynthesis. [electronic resource]
Producer: 20200416Description: 2257-2265.e4 p. digitalISSN:- 2211-1247
- Adult
- Aged
- Aged, 80 and over
- Aspartate Aminotransferase, Cytoplasmic -- metabolism
- Aspartate Aminotransferase, Mitochondrial -- metabolism
- Aspartic Acid -- biosynthesis
- Carcinoma, Renal Cell -- enzymology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Female
- Glutamine -- metabolism
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- metabolism
- Kidney Neoplasms -- enzymology
- Male
- Middle Aged
- Mitochondrial Proteins -- antagonists & inhibitors
- Neoplasms -- metabolism
- Oxidation-Reduction
- Tumor Suppressor Proteins -- metabolism
- Von Hippel-Lindau Tumor Suppressor Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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