Results
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1.
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2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1γ) inhibitors. [electronic resource] by
- Hua, Zihao
- Huang, Xin
- Bregman, Howard
- Chakka, Nagasree
- DiMauro, Erin F
- Doherty, Elizabeth M
- Goldstein, Jon
- Gunaydin, Hakan
- Huang, Hongbing
- Mercede, Stephanie
- Newcomb, John
- Patel, Vinod F
- Turci, Susan M
- Yan, Jie
- Wilson, Cindy
- Martin, Matthew W
Producer: 20130107
In:
Bioorganic & medicinal chemistry letters vol. 22
Availability: No items available.
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2.
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Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties. [electronic resource] by
- Martin, Matthew W
- Newcomb, John
- Nunes, Joseph J
- Bemis, Jean E
- McGowan, David C
- White, Ryan D
- Buchanan, John L
- DiMauro, Erin F
- Boucher, Christina
- Faust, Theodore
- Hsieh, Faye
- Huang, Xin
- Lee, Josie H
- Schneider, Stephen
- Turci, Susan M
- Zhu, Xiaotian
Producer: 20070530
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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3.
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N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SAR. [electronic resource] by
- Deak, Holly L
- Newcomb, John R
- Nunes, Joseph J
- Boucher, Christina
- Cheng, Alan C
- DiMauro, Erin F
- Epstein, Linda F
- Gallant, Paul
- Hodous, Brian L
- Huang, Xin
- Lee, Josie H
- Patel, Vinod F
- Schneider, Stephen
- Turci, Susan M
- Zhu, Xiaotian
Producer: 20080324
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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4.
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Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors. [electronic resource] by
- Bregman, Howard
- Chakka, Nagasree
- Guzman-Perez, Angel
- Gunaydin, Hakan
- Gu, Yan
- Huang, Xin
- Berry, Virginia
- Liu, Jingzhou
- Teffera, Yohannes
- Huang, Liyue
- Egge, Bryan
- Mullady, Erin L
- Schneider, Steve
- Andrews, Paul S
- Mishra, Ankita
- Newcomb, John
- Serafino, Randy
- Strathdee, Craig A
- Turci, Susan M
- Wilson, Cindy
- DiMauro, Erin F
Producer: 20130820
In:
Journal of medicinal chemistry vol. 56
Availability: No items available.
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5.
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Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: development of an expedient and divergent synthetic route and preliminary SAR. [electronic resource] by
- DiMauro, Erin F
- Newcomb, John
- Nunes, Joseph J
- Bemis, Jean E
- Boucher, Christina
- Buchanan, John L
- Buckner, William H
- Cheng, Alan
- Faust, Theodore
- Hsieh, Faye
- Huang, Xin
- Lee, Josie H
- Marshall, Teresa L
- Martin, Matthew W
- McGowan, David C
- Schneider, Stephen
- Turci, Susan M
- White, Ryan D
- Zhu, Xiaotian
Producer: 20070530
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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6.
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Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors. [electronic resource] by
- Hua, Zihao
- Bregman, Howard
- Buchanan, John L
- Chakka, Nagasree
- Guzman-Perez, Angel
- Gunaydin, Hakan
- Huang, Xin
- Gu, Yan
- Berry, Virginia
- Liu, Jingzhou
- Teffera, Yohannes
- Huang, Liyue
- Egge, Bryan
- Emkey, Renee
- Mullady, Erin L
- Schneider, Steve
- Andrews, Paul S
- Acquaviva, Lisa
- Dovey, Jennifer
- Mishra, Ankita
- Newcomb, John
- Saffran, Douglas
- Serafino, Randy
- Strathdee, Craig A
- Turci, Susan M
- Stanton, Mary
- Wilson, Cindy
- Dimauro, Erin F
Producer: 20140304
In:
Journal of medicinal chemistry vol. 56
Availability: No items available.
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7.
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Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity. [electronic resource] by
- Martin, Matthew W
- Newcomb, John
- Nunes, Joseph J
- Boucher, Christina
- Chai, Lilly
- Epstein, Linda F
- Faust, Theodore
- Flores, Sylvia
- Gallant, Paul
- Gore, Anu
- Gu, Yan
- Hsieh, Faye
- Huang, Xin
- Kim, Joseph L
- Middleton, Scot
- Morgenstern, Kurt
- Oliveira-dos-Santos, Antonio
- Patel, Vinod F
- Powers, David
- Rose, Paul
- Tudor, Yanyan
- Turci, Susan M
- Welcher, Andrew A
- Zack, Debra
- Zhao, Huilin
- Zhu, Li
- Zhu, Xiaotian
- Ghiron, Chiara
- Ermann, Monika
- Johnston, David
- Saluste, Carl-Gustaf Pierre
Producer: 20080611
In:
Journal of medicinal chemistry vol. 51
Availability: No items available.
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8.
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Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors. [electronic resource] by
- Buchanan, John L
- Newcomb, John R
- Carney, David P
- Chaffee, Stuart C
- Chai, Lilly
- Cupples, Rod
- Epstein, Linda F
- Gallant, Paul
- Gu, Yan
- Harmange, Jean-Christophe
- Hodge, Kathy
- Houk, Brett E
- Huang, Xin
- Jona, Janan
- Joseph, Smriti
- Jun, H Toni
- Kumar, Rakesh
- Li, Chun
- Lu, John
- Menges, Tom
- Morrison, Michael J
- Novak, Perry M
- van der Plas, Simon
- Radinsky, Robert
- Rose, Paul E
- Sawant, Satin
- Sun, Ji-Rong
- Surapaneni, Sekhar
- Turci, Susan M
- Xu, Keyang
- Yanez, Evelyn
- Zhao, Huilin
- Zhu, Xiaotian
Producer: 20110719
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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9.
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Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation. [electronic resource] by
- DiMauro, Erin F
- Newcomb, John
- Nunes, Joseph J
- Bemis, Jean E
- Boucher, Christina
- Chai, Lilly
- Chaffee, Stuart C
- Deak, Holly L
- Epstein, Linda F
- Faust, Ted
- Gallant, Paul
- Gore, Anu
- Gu, Yan
- Henkle, Brad
- Hsieh, Faye
- Huang, Xin
- Kim, Joseph L
- Lee, Josie H
- Martin, Matthew W
- McGowan, David C
- Metz, Daniela
- Mohn, Deanna
- Morgenstern, Kurt A
- Oliveira-dos-Santos, Antonio
- Patel, Vinod F
- Powers, David
- Rose, Paul E
- Schneider, Stephen
- Tomlinson, Susan A
- Tudor, Yan-Yan
- Turci, Susan M
- Welcher, Andrew A
- Zhao, Huilin
- Zhu, Li
- Zhu, Xiaotian
Producer: 20080611
In:
Journal of medicinal chemistry vol. 51
Availability: No items available.
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10.
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Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity. [electronic resource] by
- DiMauro, Erin F
- Newcomb, John
- Nunes, Joseph J
- Bemis, Jean E
- Boucher, Christina
- Buchanan, John L
- Buckner, William H
- Cee, Victor J
- Chai, Lilly
- Deak, Holly L
- Epstein, Linda F
- Faust, Ted
- Gallant, Paul
- Geuns-Meyer, Stephanie D
- Gore, Anu
- Gu, Yan
- Henkle, Brad
- Hodous, Brian L
- Hsieh, Faye
- Huang, Xin
- Kim, Joseph L
- Lee, Josie H
- Martin, Matthew W
- Masse, Craig E
- McGowan, David C
- Metz, Daniela
- Mohn, Deanna
- Morgenstern, Kurt A
- Oliveira-dos-Santos, Antonio
- Patel, Vinod F
- Powers, David
- Rose, Paul E
- Schneider, Stephen
- Tomlinson, Susan A
- Tudor, Yan-Yan
- Turci, Susan M
- Welcher, Andrew A
- White, Ryan D
- Zhao, Huilin
- Zhu, Li
- Zhu, Xiaotian
Producer: 20061024
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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11.
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Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity. [electronic resource] by
- Martin, Matthew W
- Newcomb, John
- Nunes, Joseph J
- McGowan, David C
- Armistead, David M
- Boucher, Christina
- Buchanan, John L
- Buckner, William
- Chai, Lilly
- Elbaum, Daniel
- Epstein, Linda F
- Faust, Theodore
- Flynn, Shaun
- Gallant, Paul
- Gore, Anu
- Gu, Yan
- Hsieh, Faye
- Huang, Xin
- Lee, Josie H
- Metz, Daniela
- Middleton, Scot
- Mohn, Deanna
- Morgenstern, Kurt
- Morrison, Michael J
- Novak, Perry M
- Oliveira-dos-Santos, Antonio
- Powers, David
- Rose, Paul
- Schneider, Stephen
- Sell, Stephanie
- Tudor, Yanyan
- Turci, Susan M
- Welcher, Andrew A
- White, Ryan D
- Zack, Debra
- Zhao, Huilin
- Zhu, Li
- Zhu, Xiaotian
- Ghiron, Chiara
- Amouzegh, Patricia
- Ermann, Monika
- Jenkins, James
- Johnston, David
- Napier, Spencer
- Power, Eoin
Producer: 20060913
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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