Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease. [electronic resource]
Producer: 20201027Description: 11392 p. digitalISSN:- 2045-2322
- Activins -- metabolism
- Animals
- Bone Morphogenetic Proteins -- metabolism
- Charcot-Marie-Tooth Disease -- drug therapy
- Disease Models, Animal
- Follistatin -- genetics
- Growth Differentiation Factors -- metabolism
- Humans
- Hypertrophy -- chemically induced
- Ligands
- Male
- Mice
- Mice, Inbred mdx
- Muscle Strength -- drug effects
- Muscle, Skeletal -- drug effects
- Muscular Dystrophy, Duchenne -- drug therapy
- Myostatin -- metabolism
- Receptors, IgG -- genetics
- Recombinant Fusion Proteins -- genetics
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Publication Type: Journal Article
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