DHEA inhibits acute microglia-mediated inflammation through activation of the TrkA-Akt1/2-CREB-Jmjd3 pathway. [electronic resource]
Producer: 20190318Description: 1410-1420 p. digitalISSN:- 1476-5578
- Animals
- CREB-Binding Protein -- metabolism
- Dehydroepiandrosterone -- pharmacology
- Inflammation -- metabolism
- Jumonji Domain-Containing Histone Demethylases -- metabolism
- Lipopolysaccharides -- pharmacology
- Male
- Mice
- Mice, Inbred C57BL
- Microglia -- drug effects
- Neuroprotective Agents -- pharmacology
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- drug effects
- Receptor, trkA -- drug effects
- Receptors, Nerve Growth Factor -- drug effects
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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