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Interspecies in vitro metabolism of the phosphodiesterase-4 (PDE4) inhibitor L-454,560. [electronic resource] by
- Bateman, Kevin P
- Trimble, Laird
- Chauret, Nathalie
- Silva, Jose
- Day, Stephen
- Macdonald, Dwight
- Dube, Daniel
- Gallant, Michel
- Mastracchio, Anthony
- Perrier, Helene
- Girard, Yves
- Nicoll-Griffith, Deborah
Producer: 20070711
In:
Journal of mass spectrometry : JMS vol. 41
Availability: No items available.
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7.
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Catalytic inactivation of protein tyrosine phosphatase CD45 and protein tyrosine phosphatase 1B by polyaromatic quinones. [electronic resource] by
- Wang, Qingping
- Dubé, Daniel
- Friesen, Richard W
- LeRiche, Tammy G
- Bateman, Kevin P
- Trimble, Laird
- Sanghara, Joe
- Pollex, Rebecca
- Ramachandran, Chidambaram
- Gresser, Michael J
- Huang, Zheng
Producer: 20040806
In:
Biochemistry vol. 43
Availability: No items available.
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8.
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Diversity in the oxidation of substrates by cytochrome P450 2D6: lack of an obligatory role of aspartate 301-substrate electrostatic bonding. [electronic resource] by
- Guengerich, F Peter
- Miller, Grover P
- Hanna, Imad H
- Martin, Martha V
- Léger, Serge
- Black, Cameron
- Chauret, Nathalie
- Silva, José M
- Trimble, Laird A
- Yergey, James A
- Nicoll-Griffith, Deborah A
Producer: 20021003
In:
Biochemistry vol. 41
Availability: No items available.
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9.
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In vitro biotransformations of the prostaglandin D2 (DP) antagonist MK-0524 and synthesis of metabolites. [electronic resource] by
- Nicoll-Griffith, Deborah A
- Seto, Carmai
- Aubin, Yves
- Lévesque, Jean François
- Chauret, Nathalie
- Day, Stephen
- Silva, José M
- Trimble, Laird A
- Truchon, Jean-François
- Berthelette, Carl
- Lachance, Nicolas
- Wang, Zhaoyin
- Sturino, Claudio
- Braun, Matt
- Zamboni, Robert
- Young, Robert N
Producer: 20070409
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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10.
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Metabolic activation of indole-containing prostaglandin D2 receptor 1 antagonists: impacts of glutathione trapping and glucuronide conjugation on covalent binding. [electronic resource] by
- Lévesque, Jean-François
- Day, Stephen H
- Chauret, Nathalie
- Seto, Carmai
- Trimble, Laird
- Bateman, Kevin P
- Silva, José M
- Berthelette, Carl
- Lachance, Nicolas
- Boyd, Michael
- Li, Lianhai
- Sturino, Claudio F
- Wang, Zhaoyin
- Zamboni, Robert
- Young, Robert N
- Nicoll-Griffith, Deborah A
Producer: 20070807
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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11.
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Structure-activity relationship studies on ortho-substituted cinnamic acids, a new class of selective EP(3) antagonists. [electronic resource] by
- Belley, Michel
- Gallant, Michel
- Roy, Bruno
- Houde, Karine
- Lachance, Nicolas
- Labelle, Marc
- Trimble, Laird A
- Chauret, Nathalie
- Li, Chun
- Sawyer, Nicole
- Tremblay, Nathalie
- Lamontagne, Sonia
- Carrière, Marie-Claude
- Denis, Danielle
- Greig, Gillian M
- Slipetz, Deborah
- Metters, Kathleen M
- Gordon, Robert
- Chan, Chi Chung
- Zamboni, Robert J
Producer: 20050607
In:
Bioorganic & medicinal chemistry letters vol. 15
Availability: No items available.
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12.
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Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: structure-activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor. [electronic resource] by
- Macdonald, Dwight
- Mastracchio, Anthony
- Perrier, Hélène
- Dubé, Daniel
- Gallant, Michel
- Lacombe, Patrick
- Deschênes, Denis
- Roy, Bruno
- Scheigetz, John
- Bateman, Kevin
- Li, Chun
- Trimble, Laird A
- Day, Stephen
- Chauret, Nathalie
- Nicoll-Griffith, Deborah A
- Silva, Jose M
- Huang, Zheng
- Laliberté, France
- Liu, Susana
- Ethier, Diane
- Pon, Doug
- Muise, Eric
- Boulet, Louise
- Chan, Chi Chung
- Styhler, Angela
- Charleson, Stella
- Mancini, Joseph
- Masson, Paul
- Claveau, David
- Nicholson, Donald
- Turner, Mervyn
- Young, Robert N
- Girard, Yves
Producer: 20060123
In:
Bioorganic & medicinal chemistry letters vol. 15
Availability: No items available.
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13.
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Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524). [electronic resource] by
- Sturino, Claudio F
- O'Neill, Gary
- Lachance, Nicolas
- Boyd, Michael
- Berthelette, Carl
- Labelle, Marc
- Li, Lianhai
- Roy, Bruno
- Scheigetz, John
- Tsou, Nancy
- Aubin, Yves
- Bateman, Kevin P
- Chauret, Nathalie
- Day, Stephen H
- Lévesque, Jean-François
- Seto, Carmai
- Silva, Jose H
- Trimble, Laird A
- Carriere, Marie-Claude
- Denis, Danielle
- Greig, Gillian
- Kargman, Stacia
- Lamontagne, Sonia
- Mathieu, Marie-Claude
- Sawyer, Nicole
- Slipetz, Deborah
- Abraham, William M
- Jones, Tom
- McAuliffe, Malia
- Piechuta, Hana
- Nicoll-Griffith, Deborah A
- Wang, Zhaoyin
- Zamboni, Robert
- Young, Robert N
- Metters, Kathleen M
Producer: 20070327
In:
Journal of medicinal chemistry vol. 50
Availability: No items available.
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