Biosynthesis of the unusual amino acid (4R)-4-[(E)-2-butenyl]-4-methyl-L-threonine of cyclosporin A: enzymatic analysis of the reaction sequence including identification of the methylation precursor in a polyketide pathway. [electronic resource]
Producer: 19960820Description: 8401-12 p. digitalISSN:- 0006-2960
- Chromatography, Thin Layer
- Coenzyme A -- metabolism
- Cyclosporine -- chemistry
- Fatty Acids, Unsaturated -- metabolism
- Magnetic Resonance Spectroscopy
- Mass Spectrometry
- Methylation
- Mitosporic Fungi -- enzymology
- Multienzyme Complexes -- drug effects
- NADP -- pharmacology
- Oxidation-Reduction
- Potentiometry
- Threonine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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