Blockade of crizotinib-induced BCL2 elevation in ALK-positive anaplastic large cell lymphoma triggers autophagy associated with cell death. [electronic resource]
Producer: 20200602Description: 1428-1439 p. digitalISSN:- 1592-8721
- Anaplastic Lymphoma Kinase -- genetics
- Animals
- Antineoplastic Agents -- pharmacology
- Autophagy
- Cell Death
- Cell Proliferation -- drug effects
- Crizotinib -- pharmacology
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Lymphoma, Large-Cell, Anaplastic -- drug therapy
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Prognosis
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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