Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations. [electronic resource]
Producer: 20190415Description: 116-126 p. digitalISSN:- 1520-5010
- Biocatalysis
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Humans
- Imines -- chemical synthesis
- Liver -- drug effects
- Molecular Structure
- NAD(P)H Dehydrogenase (Quinone) -- antagonists & inhibitors
- Oxidation-Reduction
- Quinone Reductases -- antagonists & inhibitors
- Quinones -- chemical synthesis
- Recombinant Proteins -- metabolism
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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